We joke around in public places.
We hit each other but we never really fight.
We dance weird to awesome songs… just for fun :)
We give eachorther the “sexy face.”
If she takes my seat…..
We give each other high fives ;)
We scare each other all the time.
I love my best friend :)
I just bought a book I’d been eyeing for a while on how to make paper flowers. Though I’m in love with all the different designs, it can be quite hard to follow some of the directions (and get some of the supplies!). Not so with Lia’s gorgeous paper flowers. Each flower has clear, step by step instructions, plus photos. And all her flowers come with free download patterns (some of them are also designed to be printed straight off with the pattern on there - bonus!). And there are lots of uses for something like this, including popping them on top of your Christmas gifts, or even attaching them to your Christmas tree - how pretty would that look!?
05 December 2013
For two centuries, scientists studying the brain focused on neurons and largely ignored neuroglia: a group of cell types that make up half our brain and spinal cord. Indeed, glial cells were considered little more than brain glue. But it’s now clear that they play an active role in brain function. Take astrocytes, for example (pictured). We now know that these cells, whose thousands of thread-like tendrils wrap around the junctions between neurons, can influence neural signaling. Researchers have also begun to explore whether astrocytes might explain why humans are more intelligent than other animals. One group showed that mice that received transplants of human astrocytes learned much more quickly than normal mice, suggesting that there may be something special about the human astrocyte (pictured right) – which is larger than the mouse version (left) – that contributes to the advanced computational abilities of the human brain.
Written by Daniel Cossins
straight up blew my mind
In Sweden this weekend, three scientists are receiving the Nobel Prize in Physiology or Medicine for their discoveries about how vesicles transport chemicals and release their cargo. A new study published in Nature has elucidated the reverse of this process: how vesicles form and import cargo via endocytosis. Researchers at the University of Utah and Charity University Medicine Berlin in Germany photographed nerve cells as vesicles released neurotransmitters into the synapse and then recycled these vesicles to absorb excess chemicals. Neurons from the mouse hippocampus were grown in culture and plated onto tiny sapphire discs. They engineered the neurons to fire when exposed to a burst of light. Immediately after flashing the light, they flash froze the cells in liquid nitrogen, sliced them thin, and viewed them under an electron microscope. The scientists found vesicles in the process of exocytosis (pictured, right, orange circles), releasing their contents (red dots) into the synapse where they travel to receptors on the next neuron (red cross-hatches). After this occurs, the vesicles re-form at the synapse (pictured, left, yellow circles) and re-enter the cell, all in less than a tenth of a second. The scientists say that it’s an extremely efficient way of allowing neurons and muscles to keep working for long periods of time.
Read more: http://bit.ly/1bP8H8p
Journal article: Ultrafast endocytosis at mouse hippocampal synapses. Nature, 2013. doi:10.1038/nature12809
Image credit: Janet Iwasa, University of Utah
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